Table 2.
Psychotropic drugs | n | % | Potentially inappropriate (%) |
---|---|---|---|
benzodiazepines | |||
lormetazepama | 403 | 18.9 | > 0,5 mg/d (97.3) |
lorazepama | 155 | 7.3 | > 2 mg/d (1.9) |
tetrazepam | 26 | 1.2 | each dose (100) |
diazepam | 25 | 1.2 | each dose (100) |
oxazepam | 25 | 1.2 | > 60 mg/d (0) |
temazepam | 15 | 0.7 | each dose (100) |
bromazepam | 12 | 0.6 | each dose (100) |
dipotassium clorazepat | 10 | 0.5 | each dose (100) |
flunitrazepam | 9 | 0.4 | each dose (100) |
alprazolam | 5 | 0.2 | each dose (100) |
brotizolam | 5 | 0.2 | > 0.125 (80) |
clonazepam | 3 | 0.1 | each dose (100) |
midazolam | 3 | 0.1 | n.a. |
nitrazepam | 2 | 0.1 | each (100) |
flurazepam | 1 | 0.1 | each dose (100) |
neuroleptics | |||
melperone | 119 | 5.6 | n.a. |
prothipendyl | 58 | 2.7 | n.a. |
quetiapine | 42 | 2.0 | n.a. |
haloperidol | 33 | 1.6 | > 2 mg/d (42.4) |
promethazine | 29 | 1.4 | n.a. |
risperidone | 20 | 0.9 | n.a. |
aripiprazole | 6 | 0.3 | n.a. |
olanzapine | 6 | 0.3 | > 10 mg/d (50) |
pipamperone | 3 | 0.1 | n.a. |
levomepromazine | 2 | 0.1 | each dose (100) |
clozapine | 2 | 0.1 | each dose (100) |
flupentixol | 1 | 0.1 | n.a. |
pimozid | 1 | 0.1 | n.a. |
sulpirid | 1 | 0.1 | n.a. |
Z-drugs | |||
zopiclone | 171 | 8.0 | > 3,75 mg/d (60.8) |
zolpidem | 112 | 5.3 | > 5 mg/d (76.8) |
antidepressants | |||
mirtazapine | 228 | 10.7 | n.a. |
citalopram | 138 | 6.5 | n.a. |
duloxetine | 47 | 2.2 | n.a. |
venlafaxine | 34 | 1.6 | n.a. |
amitriptyline | 31 | 1.5 | each dose (100) |
doxepine | 22 | 1.0 | each dose (100) |
sertraline | 14 | 0.7 | n.a. |
trimipramine | 12 | 0.6 | each dose (100) |
escitalopram | 10 | 0.5 | n.a. |
opipramol | 9 | 0.4 | n.a. |
trazodone | 5 | 0.2 | n.a. |
maprotiline | 5 | 0.2 | each dose (100) |
fluoxetine | 5 | 0.2 | each dose (100) |
paroxetine | 5 | 0.2 | n.a. |
clomipramine | 4 | 0.2 | each dose (100) |
bupropion | 4 | 0.2 | n.a. |
agomelatin | 2 | 0.1 | n.a. |
mianserin | 2 | 0.1 | n.a. |
imipramine | 2 | 0.1 | each dose (100) |
fluvoxamine | 1 | 0.1 | n.a. |
% of potentially inappropriate refers to patients receiving the respective psychotropic drug
aAverage daily doses [mg] of the psychotropic drugs most frequently prescribed (medians). Lormetazepam: 1.0; lorazepam: 1.0; zopiclone 7.5; zolpidem 10.0; mirtazapine: 15; citalopram: 20; melperone: 25; prothipendyl: 50