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. 2017 Dec 4;18:76. doi: 10.1186/s40360-017-0183-0

Table 2.

Prevalence of all psychotropic drugs prescribed in the period studied

Psychotropic drugs n % Potentially inappropriate (%)
benzodiazepines
 lormetazepama 403 18.9 > 0,5 mg/d (97.3)
 lorazepama 155 7.3 > 2 mg/d (1.9)
 tetrazepam 26 1.2 each dose (100)
 diazepam 25 1.2 each dose (100)
 oxazepam 25 1.2 > 60 mg/d (0)
 temazepam 15 0.7 each dose (100)
 bromazepam 12 0.6 each dose (100)
 dipotassium clorazepat 10 0.5 each dose (100)
 flunitrazepam 9 0.4 each dose (100)
 alprazolam 5 0.2 each dose (100)
 brotizolam 5 0.2 > 0.125 (80)
 clonazepam 3 0.1 each dose (100)
 midazolam 3 0.1 n.a.
 nitrazepam 2 0.1 each (100)
 flurazepam 1 0.1 each dose (100)
neuroleptics
 melperone 119 5.6 n.a.
 prothipendyl 58 2.7 n.a.
 quetiapine 42 2.0 n.a.
 haloperidol 33 1.6 > 2 mg/d (42.4)
 promethazine 29 1.4 n.a.
 risperidone 20 0.9 n.a.
 aripiprazole 6 0.3 n.a.
 olanzapine 6 0.3 > 10 mg/d (50)
 pipamperone 3 0.1 n.a.
 levomepromazine 2 0.1 each dose (100)
 clozapine 2 0.1 each dose (100)
 flupentixol 1 0.1 n.a.
 pimozid 1 0.1 n.a.
 sulpirid 1 0.1 n.a.
Z-drugs
 zopiclone 171 8.0 > 3,75 mg/d (60.8)
 zolpidem 112 5.3 > 5 mg/d (76.8)
antidepressants
 mirtazapine 228 10.7 n.a.
 citalopram 138 6.5 n.a.
 duloxetine 47 2.2 n.a.
 venlafaxine 34 1.6 n.a.
 amitriptyline 31 1.5 each dose (100)
 doxepine 22 1.0 each dose (100)
 sertraline 14 0.7 n.a.
 trimipramine 12 0.6 each dose (100)
 escitalopram 10 0.5 n.a.
 opipramol 9 0.4 n.a.
 trazodone 5 0.2 n.a.
 maprotiline 5 0.2 each dose (100)
 fluoxetine 5 0.2 each dose (100)
 paroxetine 5 0.2 n.a.
 clomipramine 4 0.2 each dose (100)
 bupropion 4 0.2 n.a.
 agomelatin 2 0.1 n.a.
 mianserin 2 0.1 n.a.
 imipramine 2 0.1 each dose (100)
 fluvoxamine 1 0.1 n.a.

% of potentially inappropriate refers to patients receiving the respective psychotropic drug

aAverage daily doses [mg] of the psychotropic drugs most frequently prescribed (medians). Lormetazepam: 1.0; lorazepam: 1.0; zopiclone 7.5; zolpidem 10.0; mirtazapine: 15; citalopram: 20; melperone: 25; prothipendyl: 50