Skip to main content
. 2017 Nov 13;114(48):E10446–E10454. doi: 10.1073/pnas.1708553114

Fig. 2.

Fig. 2.

LegC4 function attenuates L. pneumophila replication in the mouse lung. (A) Enumeration of WT, legC4::Tn, or ∆legC4 from lungs of NLRC4−/− mice. (B) CI of legC4::Tn versus WT from the lungs of NLRC4−/− mice. (C) CI of legC4::Tn (pV) or legC4::Tn (plegC4) versus WT (pV) in the lungs of NLRC4−/− mice. Each symbol represents an individual animal, and asterisks denote statistical significance by Mann–Whitney U test (*P < 0.05, **P < 0.01). (D) ELISA for IL-12 p40 secretion from NLRC4−/− BMDMs infected with the indicated strains. Data are presented as mean ± SD, and asterisks denote statistical significance (**P < 0.01; n.s., not significant). Data are representative of at least two independent experiments.