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. 2017 Nov 13;114(48):E10349–E10358. doi: 10.1073/pnas.1710298114

Fig. 5.

Fig. 5.

Stem mismatch does not impact downstream of AGO. (A) Schematic of the RNAi pathway. A Dicer product bearing the same mismatch variation as the Dicer substrate is applied to the silencing assay. (B) mRNA histogram for Dicer product with varying mismatches. (C) Silencing efficiency induced by the Dicer product with the stem mismatches. (D) Silencing efficiency of the Dicer product with varying mismatches plotted against the silencing efficiency of the Dicer substrate with the same mismatches.