Table 1.
Utility and limitations of measurements of serum anti‐Müllerian hormone (AMH) levels in various clinical conditions
What have we learned? | What should we know? | |
---|---|---|
Medically assisted reproduction | Good correlation to oocyte yield Predictive potential for poor and hyper‐response | Predictive potential for live births Optimization of protocols to improve treatment success |
General population | Peaks around 25 years of age and gradually declines Very low serum AMH level does not necessarily mean sterility | Predictive potential for future fertility |
Menopause/POI | Undetectable serum AMH level is followed by menopause within a certain time period depending on age | Selection and diagnosis of subclinical POI |
PCOS | Elevated serum AMH level is correlated with severity | Association with pathophysiology Optimization of treatment schedules according to serum AMH levels |
Ovarian toxicity/surgical intervention | Decline depending on chemotherapeutic regimens and surgical interventions, especially cystectomy for endometriomas | Indication of fertility preservation Optimal interventions according to ovarian reserve |
POI primary ovarian insufficiency, PCOS polycystic ovary syndrome