Table 2.
Clinical outcomes of in vitro fertilization
| Variable | Group A (FP) | Group B1 (no FP/no chemotherapy) | Group B2 (no FP/postchemotherapy) |
|---|---|---|---|
| No. of patients | 21 | 13 | 8 |
| No. of OPU cycles | 28 | 21 | 33 |
| Age at first admission (years) | 35.19 ± 3.14a | 38.69 ± 5.39 | 40.50 ± 2.56a |
| Age at cancer diagnosis (years) | 34.81 ± 3.27 | 35.82 ± 6.79 | 33.00 ± 4.75 |
| Body mass index (kg/m2) | 20.00 ± 1.70 | 21.50 ± 3.10 | 20.20 ± 3.30 |
| Serum AMH level (ng/mL) | 3.56 ± 4.01 | 3.48 ± 2.66 | 1.34 ± 1.09 |
| Peak serum E2 level(pg/mL) | 887.93 ± 800.03 | 1211.08 ± 1017.97a | 504.82 ± 423.82a |
| No. of collected oocytes | 6.86 ± 5.62a | 5.76 ± 4.95b | 2.42 ± 2.54a , b |
| No. of MII oocytes | 4.89 ± 3.96a | 5.14 ± 4.21c | 1.97 ± 2.27a , c |
| No. of vitrified oocytes | 5.44 ± 4.20 | N/A | N/A |
| No. of fertilized oocytes | 2.95 ± 2.95 | 3.86 ± 3.68b | 1.39 ± 1.64b |
| No. of cryopreserved embryos | 2.24 ± 2.11d | 2.00 ± 2.83b | 0.24 ± 0.50b , d |
| No. (%) of patients with past radiation therapy | N/A | 11 (84.6)e | 5 (62.5)e |
| No. (%) of patients with past hormonal therapy | N/A | 4 (30.8)f | 6 (75.0)f |
AMH, anti‐Müllerian hormone; E2, estradiol; FP, fertility preservation; MII, metaphase II; N/A, not applicable; OPU, oocyte pick‐up. a P < .001; b P < .01; c P < .001; d P < .002, according to the Mann‐Whitney U‐test; e P = .33; f P = .08, according to Fisher's exact test.