Fig. 1.

APS inhibits A549 and NCI-H358 cell growth in a concentration- and time-dependent manner. A549 cells were treated with different concentration of APS for 24 h a and with 20 mg/mL APS for different time b, NCI-H358 cells were treated with different concentration of APS for 24 h c and with 20 mg/mL APS for different time d. The growth inhibition of 20 mg/mL APS on A549 and NCI-H358 cells with or without the 12 h pre-incubation of the NF-κB activator PMA or NF-κB inhibitor Bay was shown in e, f respectively. Representative data of three independent experiments are shown