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. 2017 Oct 27;45(21):12057–12068. doi: 10.1093/nar/gkx990

Figure 3.

Figure 3.

Different stoichiometries of the DNA/αHL hybrid pores investigated in this study. (A) Comparison of the dimensions of a (i) heptameric, (ii) dodecameric, (iii) icosameric and (iv) hexacosameric αHL pore based on a monomer width of 33.8 Å. (B) Example TEM micrographs of liposomes-adhered DNA-modified K237C-αHL mutants in (i) the absence of a DNA structure, or assembled along a circular DNA with (ii) 12, (iii) 20, and (iv) 26, sequence segments. Scale bar in (i) is 10 nm and applies to all images. (C) Conductance dependence on pore stoichiometry of DNA-modified K237C-αHL mutants. (D) Conductance histogram for the different DNA/αHL hybrid pores.