Table 1. Level of support by MRPP1/2 on ELAC2 mediated 3′-tail removal.

heavy-strand:		light-strand:
tRNA	Effect of MRPP1/2	tRNA	Effect of MRPP1/2
Phe(0,15)	+	Pro(0,15)	++
Val(0,15)	++	Glu(0,15)	++
LeuUUR(0,15)	+/-	SerUCN(0,15)	+/-
Ile(0,15)	+	Tyr(0,17)	++
Met(0,15)	+	Cys(0,15)	++
Trp(0,15)	++	Asn(0,15)	+/-
Asp(0,15)	++	Ala(0,15)	++
Lys(0,15)	++	Gln(0,15)	+/-
Gly(0,15)	+
Arg(0,15)	++
His(0,S)a	++
SerAGY(0,L1+15)b	- -
LeuCUN(0,15)	+
Thr(0,15)	++

++strong enhancement of ELAC2 efficiency in presence of MRPP1/2.

+moderate enhancement of ELAC2 efficiency in presence of MRPP1/2.

+/-no significant difference in ELAC2 efficiency in the absence or presence of MRPP1/2.

- -strong decrease of ELAC2 efficiency in presence of MRPP1/2.

^aS, Ser^AGY

^bL₁, Leu^CUN

See also Supplementary Figure S1.