Fig. 2.

Reduced negative functional connectivity between the left BLA and left DLPFC in veterans suffering from impulsive aggression problems. A. For visualization purposes, the top and middle panel show the whole-brain FWE-significant connectivity patterns with the left BLA seed, for the impulsive aggression (cut-off = 5.774) and combat control groups (cut-off = 5.668), respectively. Note: voxels in the immediate proximity of the seed-region were set to zero for purposes of visualization and scaling. Cluster-based analysis revealed significant group-differences in the left DLPFC (bottom panel; voxel-level p-value < 0.005, k ≥ 20). B. Mean (negative) β-weight values were observed to be diminished in the impulsive aggression group (mean β-weight = -0.021 ± 0.014), relative to the combat control group (mean β-weight = -0.082 ± 0.022)