Table 1.
Patient data, CSF
| Lymphoma Patients | Controls | ||||||
|---|---|---|---|---|---|---|---|
| PCNSL/ Activea (n = 33) |
SCNSL (n = 6) |
PBT (n = 20) |
SBTb (n = 22) |
Neuroinf. (n = 13) |
Neuroinflamm.c (n = 30) |
ONDsd (n = 52) |
|
| Sex F/M | 14/19 | 1/5 | 6/14 | 12/10 | 3/10 | 18/12 | 30/22 |
| Mean age ± SD (range) | 65 ± 15 (21–89) |
62 ± 19 (33–90) |
54 ± 19 (21–83) |
64 ± 14 (31–84) |
56 ± 15 (30–81) |
43 ± 14 (19–73) |
49 ± 22 (18–85) |
| Mean CSF cell count, cells/µL ± SD (range) | 38 ± 83 (1–408) |
95 ± 148 (2–369) |
12 ± 45 (0–204) |
19 ± 33 (0–132) |
882 ± 2349 (1–8846) |
21 ± 38 (0–144) |
2 ± 1 (0–7) |
| Mean CSF total protein, mg/dL ± SD (range) | 106 ± 124 (9–604) |
101 ± 60 (56–211) |
64 ± 32 (25–160) |
90 ± 81 (15–336) |
137 ± 93 (44–376) |
59 ± 25 (24–116) |
44 ± 16 (22–83) |
| Mean CSF glucose, mg/ dL ± SD (range) | 64 ± 16 (10–93) |
58 ± 18 (34–88) |
62 ± 8 (53–89) |
60 ± 20 (10–98) |
59 ± 18 (32–99) |
63 ± 10 (51–101) |
64 ± 11 (45–104) |
| Mean albumin quotient ± SD (range) | 19 ± 23 (3–96) |
26 ± 23 (12–53) |
9 ± 6 (2–22) |
17 ± 18 (4–55) |
17 ± 18 (4–65) |
7 ± 4 (2–19) |
6 ± 3 (3–12) |
Abbreviations: neuroinf. = neuroinfectious disease; neuroinflamm. = neuroinflammatory disease.
aTwenty-six patients with sampling at the time of diagnosis, 7 patients with sampling during disease relapse.
bSix patients with brain metastases without meningeosis, 10 patients with brain metastases and meningeosis, 6 patients with meningeosis without solid metastases.
cEleven patients with multiple sclerosis, 7 patients with other inflammatory neurological diseases, 5 patients with clinically isolated syndrome, 2 patients with neuromyelitis spectrum disorder, 1 patient with acute demyelinating encephalomyelitis, 1 patient with cerebral vasculitis, 1 patient with neurosarcoidosis, 1 patient with Sjogren’s syndrome, 1 patient with Miller–Fisher syndrome.
dTwenty patients with headache, 4 patients with neurodegenerative diseases, 3 patients with epilepsia, 2 patients with normal pressure hydrocephalus, 4 patients with Bell’s palsy, 8 patients with peripheral neuropathies, 4 patients with ischemia, 1 patient with hypersomnia, 1 patient with narcolepsia, 1 patient with chronic pain, 1 patient with arthritis, 1 patient with metabolic encephalopathy, 2 patients with myasthenia gravis.