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Chronic ethanol intake impairs demethylation pathways. mRNA levels of Ten-Eleven Translocase (TET) 1, 2, and 3, as well as Growth Arrest and DNA Damage Inducible Beta (GADD45B) and Apolipoprotein B mRNA editing enzyme catalytic subunit 3C (APOBEC 3C) are expressed as fold change of controls. Values are mean ± SEM of 24 samples per group. *P < .05, Student’s t test vs controls.
