Table 2.
Association of p-STAT3 expression with clinicopathological factors in UBC patients
| Category | All cases, n (%) | p-STAT3, n (%)
|
P-value | |
|---|---|---|---|---|
| Low | High | |||
| Age | 0.016 | |||
| <65 years | 31 (40.3) | 14 (45.2) | 17 (54.8) | |
| ≥65 years | 46 (59.7) | 9 (19.6) | 37 (80.4) | |
| Sex | 0.345 | |||
| Male | 70 (90.9) | 22 (31.4) | 48 (68.6) | |
| Female | 7 (9.1) | 1 (14.3) | 6 (85.7) | |
| Tumor grade | 0.009 | |||
| Low | 24 (31.2) | 12 (50.0) | 12 (50.0) | |
| High | 53 (68.8) | 11 (20.8) | 42 (79.2) | |
| Tumor stage | 0.010 | |||
| Ta+T1 | 27 (35.1) | 13 (48.1) | 14 (51.9) | |
| T2+T3+T4 | 50 (64.9) | 10 (20.0) | 40 (80.0) | |
| Tumor size | 0.162 | |||
| ≥2 cm | 59 (76.6) | 20 (33.9) | 39 (66.1) | |
| >2 cm | 18 (23.4) | 3 (16.7) | 15 (83.3) | |
| Tumor number | 0.010 | |||
| Single | 68 (88.3) | 17 (25.0) | 51 (75.0) | |
| Multiple | 9 (11.7) | 6 (66.7) | 3 (33.3) | |
| Nerve invasion | 0.580 | |||
| Yes | 20 (26.0) | 18 (31.6) | 39 (68.4) | |
| No | 57 (74.0) | 5 (25.0) | 15 (75.0) | |
| Lymphovascular invasion | 0.088 | |||
| Yes | 24 (31.2) | 4 (16.7) | 20 (83.3) | |
| No | 53 (68.8) | 19 (35.8) | 34 (64.2) | |
| Nodal metastasis | 0.212 | |||
| Yes | 17 (22.1) | 3 (17.6) | 14 (82.4) | |
| No | 60 (77.9) | 20 (33.3) | 40 (66.7) | |
| TNM stage | 0.707 | |||
| 0+1+2 | 41 (53.2) | 13 (31.7) | 28 (68.3) | |
| 3+4 | 36 (46.8) | 10 (27.8) | 26 (72.2) | |
| DAB2IP | 0.009 | |||
| Positive | 24 (31.2) | 12 (50.0) | 12 (50.0) | |
| Negative | 53 (68.8) | 11 (20.8) | 42 (79.2) | |
| Total | 77 (100) | 23 (29.9) | 54 (70.1) | |
Note: Bold values are statistically significant (P<0.05).
Abbreviation: UBC, urothelial carcinoma of the bladder.