Table 5.
Dynamometric parameters and 6MWT in COPD groups divided according to combined COPD assessment
| Dynamometric parameters | Control (n=25) |
Group A (n=3) |
Group B (n=24) |
Group D (n=31) |
A/K-W |
|---|---|---|---|---|---|
| Max grip (N) | 371±90 | 369±124 | 332±82 | 298±88a | 0.210 |
| Scored time (s) | 104 (88; 128) | 123 (83; 147) | 91 (69; 108) | 77 (62; 89)a | 0.075 |
| AUC (thousands) | 18.9 (16.0; 24.2) | 18.4 (14.2; 30.6) | 15.4 (11.8; 7.1)a,b | 11.9 (10.9; 13.8)a,b | 0.004 |
| AUC/kg | 223 (198; 263) | 185 (136; 311) | 176 (137; 236) | 170 (121; 191)a | 0.454 |
| AUC/kg FFM | 314 (276; 367) | 280 (229; 450) | 245 (190; 330) | 228 (175; 264)a | 0.172 |
| 6MWT (m) | 537 (484; 564) | 420 (390; 420) | 410 (360; 450)a | 360 (300; 420)a | 0.057 |
Notes: A/K-W, P-value of one-way analysis of variance or Kruskal–Wallis test, bolded values reached statistical significance (P≤0.05). Results are expressed as mean ± SD or median (25th percentile; 75th percentile).
t-Test, Mann–Whitney U-test, or Wilcoxon signed rank test vs control group (P≤0.05);
t-test or Mann–Whitney U-test vs Group A (P≤0.05). Values of 6MWT for the control group were calculated using reference equations for healthy adults.14
Abbreviations: 6MWT, 6-minute walk test; AUC, area under the force/time curve; FFM, fat-free mass; Max grip, maximum hand grip strength of dominant arm; Scored time, elapsed time of endurance test in targeted range only.