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. 2017 Oct 5;40(6):1719–1730. doi: 10.3892/ijmm.2017.3174

Table V.

Crucial GO functions in the microRNA-GO-network (degree >15).

GO (name) Degree
Gene expression 21
Positive regulation of transcription, DNA-dependent 21
Positive regulation of transcription from RNA polymerase II promoter 20
Signal transduction 20
Negative regulation of transcription from RNA polymerase II promoter 19
Small molecule metabolic process 19
Transforming growth factor-β receptor signaling pathway 19
Axon guidance 18
Innate immune response 18
Transcription, DNA-dependent 18
Virus-host interaction 17
Negative regulation of apoptotic process 16
Negative regulation of transcription, DNA-dependent 16
Regulation of transcription, DNA-dependent 16
Synaptic transmission 16
Transcription initiation from RNA polymerase II promoter 16
Heart development 15
Mitotic cell cycle 15
Positive regulation of cell proliferation 15
Protein phosphorylation 15

GO, Gene Ontology.