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. 2017 Sep 27;40(6):1657–1668. doi: 10.3892/ijmm.2017.3153

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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CSPG-induced inhibition of OPC maturation is associated with β1-integrin. (A) Western blotting and (B) western blot quantification revealed that the protein level of β1-integrin was significantly decreased in CSPG-treated OPCs compared with the control at 3 and 5 days following treatment. (C) The mRNA expression level of β1-integrin was also significantly reduced compared with the control in CSPG-treated OPCs after 3 and 5 days. ^*P<0.05 and ^**P<0.01 vs. the control group. CSPG, chondroitin sulfate proteoglycan; OPC, oligodendrocyte precursor cell.