a CD1b monomers were treated with methoxy MA at several molar ratios in buffers containing the indicated percentages of CHAPS detergent, tetramerized using streptavidin-allophycocyanin, and used to stain the indicated T cell line or clone. b Using a 5:1 molar ratio and 0.6% CHAPS, methoxy-, α-, or keto MA were loaded into CD1b tetramers and used to stain the indicated T cell line or clone. Stainings in b and c were performed twice independently. Staining of GEM18 was performed three times independently.