Table 1. Baseline characteristics of population study.

	RFH (n = 98)		BJH (n = 54)		p value
Age (years)	37.6	±13.4	39.3	±13.4	NS
Sex (Female)	65	66.3%	35	64.8%	NS
KCH (yes)	83	84.7%	43	79.6%	NS
LT	19	19.4%	28	51.9%	<0.001
3-months mortality	38	38.8%	18	33.3%	NS
Days to death from admission	8	0–92	1	0–52	0.002
Grade HE 3–4	63	64.3%	36	66.7%	NS
Vasopressor use	60	61.2%	26	48.1%	NS
Renal replacement therapy	61	62.2%	31	57.4%	NS
Mechanical ventilation	66	67.3%	29	53.7%	NS
Body temperature (°C)	36.5	31–39.2	36.9	32.9–39.0	NS
Heart rate (bpm)	120	32–165	110	60–160	0.003
Mean arterial pressure (mmHg)	63	43–97	73	35–123	0.002
PCO2 (kPa)	4.5	2–8.7	3.9	1.3–6.0	<0.001
PaO2 (kPa)	13.8	6.3–36.7	15.4	6.9–35.3	NS
FiO2 (%)	30	21–100	21	21–100	NS
PaO2/FiO2 (kPa)	50	12.8–110.2	53	8.3–151	NS
A-a Gradient (mmHg)	65.1	-79.2–563.2	39.2	-88.3–636	NS
Norepinephrine dose (mcg/min)	0.0	0–130	15	0–265.6	0.004
Ammonia (umol/L)	98	35–286	300	50–999	<0.001
Platelets (10^9/L)	80.5	6–288	121.5	9–461	<0.001
Creatinine (umol/L)	226.5	43–825	145.5	49–564	NS
Urea (mmol/L)	8	1.8–46.9	5.7	1.2–17.8	0.005
Total Bilirubin (umol/L)	88	3–581	67.5	8–492	NS
INR	8	1.2–16	6.9	2.2–11.9	NS
pH	7.34	6.93–7.51	7.36	6.92–7.52	NS
Sodium (mmol/L)	129.8	± 7.22	136.7	±6.21	NS
HCO3 (mmol/L)	19.1	±5.22	15.6	±5.80	NS
Lactate (mmol/L)	4.8	0.8–35.8	8.6	1.1–24.9	0.009

Variables are expressed as numbers and percentages or mean ± standard deviation (or median and range when appropriate). KCH, King’s College Hospital criteria; LT, liver transplantation; HE, hepatic encephalopathy; INR, international normalized ratio.