Table 1. Baseline characteristics of population study.
RFH (n = 98) | BJH (n = 54) | p value | |||
---|---|---|---|---|---|
Age (years) | 37.6 | ±13.4 | 39.3 | ±13.4 | NS |
Sex (Female) | 65 | 66.3% | 35 | 64.8% | NS |
KCH (yes) | 83 | 84.7% | 43 | 79.6% | NS |
LT | 19 | 19.4% | 28 | 51.9% | <0.001 |
3-months mortality | 38 | 38.8% | 18 | 33.3% | NS |
Days to death from admission | 8 | 0–92 | 1 | 0–52 | 0.002 |
Grade HE 3–4 | 63 | 64.3% | 36 | 66.7% | NS |
Vasopressor use | 60 | 61.2% | 26 | 48.1% | NS |
Renal replacement therapy | 61 | 62.2% | 31 | 57.4% | NS |
Mechanical ventilation | 66 | 67.3% | 29 | 53.7% | NS |
Body temperature (°C) | 36.5 | 31–39.2 | 36.9 | 32.9–39.0 | NS |
Heart rate (bpm) | 120 | 32–165 | 110 | 60–160 | 0.003 |
Mean arterial pressure (mmHg) | 63 | 43–97 | 73 | 35–123 | 0.002 |
PCO2 (kPa) | 4.5 | 2–8.7 | 3.9 | 1.3–6.0 | <0.001 |
PaO2 (kPa) | 13.8 | 6.3–36.7 | 15.4 | 6.9–35.3 | NS |
FiO2 (%) | 30 | 21–100 | 21 | 21–100 | NS |
PaO2/FiO2 (kPa) | 50 | 12.8–110.2 | 53 | 8.3–151 | NS |
A-a Gradient (mmHg) | 65.1 | -79.2–563.2 | 39.2 | -88.3–636 | NS |
Norepinephrine dose (mcg/min) | 0.0 | 0–130 | 15 | 0–265.6 | 0.004 |
Ammonia (umol/L) | 98 | 35–286 | 300 | 50–999 | <0.001 |
Platelets (10^9/L) | 80.5 | 6–288 | 121.5 | 9–461 | <0.001 |
Creatinine (umol/L) | 226.5 | 43–825 | 145.5 | 49–564 | NS |
Urea (mmol/L) | 8 | 1.8–46.9 | 5.7 | 1.2–17.8 | 0.005 |
Total Bilirubin (umol/L) | 88 | 3–581 | 67.5 | 8–492 | NS |
INR | 8 | 1.2–16 | 6.9 | 2.2–11.9 | NS |
pH | 7.34 | 6.93–7.51 | 7.36 | 6.92–7.52 | NS |
Sodium (mmol/L) | 129.8 | ± 7.22 | 136.7 | ±6.21 | NS |
HCO3 (mmol/L) | 19.1 | ±5.22 | 15.6 | ±5.80 | NS |
Lactate (mmol/L) | 4.8 | 0.8–35.8 | 8.6 | 1.1–24.9 | 0.009 |
Variables are expressed as numbers and percentages or mean ± standard deviation (or median and range when appropriate). KCH, King’s College Hospital criteria; LT, liver transplantation; HE, hepatic encephalopathy; INR, international normalized ratio.