Table 3. Performance of main prognostic scores in predicting 3-month mortality in not-transplanted (NOLT) and transplanted (LT) patients (RFH cohort).

NOLT	AUC	p	cut-off	HR	Sensitivity	Specificity	PPV	NPV
MELD	0.671	0.007	33.4	2.595	74.2	54.2	51.1	76.5
UKELD	0.674	0.006	71	2.127	54.8	72.9	56.5	71.4
APACHE 2	0.757	<0.001	18	13.572	96.8	45.8	53.5	95.6
APACHE 3	0.740	<0.001	101	35.870	100	41.6	52.4	100
SOFA	0.799	<0.001	11	5.2	77.4	70.8	63.1	82.9
KCH	0.638	0.005	y	3.28	83.9	43.7	49	80.8
CLIF-C OF	0.793	<0.001	12	38.914	93.5	58.3	59.1	93.2
CLIF-C ACLF	0.762	<0.001	46	9.059	93.5	52.1	55.7	92.5
LT	AUC	p	cut-off	HR	Sensitivity	Specificity	PPV	NPV
MELD	0.564	NS	40.7	2.952	33.3	100	100	76.4
UKELD	0.724	NS	74	0.298	100	38.5	42.8	100
APACHE 2	0.558	NS	32	3.093	50	84.6	59.9	78.5
APACHE 3	0.557	NS	140	2.305	66.6	69.2	49.9	81.7
SOFA	0.532	NS	9	0.69	33.3	92.3	66.6	74.9
KCH	0.628	NS	n	0.409	33.3	92.3	66.6	74.9
CLIF-C OF	0.577	NS	16	0.513	100	15.4	35.3	100
CLIF-C ACLF	0.660	NS	60	0.386	100	38.5	42.8	100

AUC: area under the curve; HR, hazard ratio; PPV, positive predictive value; NPV, negative predictive value; MELD, model for end-stage liver disease; UKELD, United Kingdom model for end-stage liver disease; APACHE, acute physiology in chronic health evaluation; SOFA, Sequential organ failure assessment; CLIF-C OF, Chronic liver failure-consortium organ failures; CLIF-C ACLF, Chronic liver failure-consortium acute on chronic liver failure.