Table 4. α4β2 binding sites by autoradiography.
| NAc | OT | ST | opt | OPN | |
| fmol of binding /mg wet weight of tissue | |||||
| lynx1WT/ α6L9′S |
2.59 ± 0.14 (n = 6) |
2.15 ± 0.16 (n = 6) |
3.49 ± 0.21 (n = 6) |
2.97 ± 0.21 (n = 6) |
7.60 ± 0.53 (n = 6) |
| lynx1KO/ α6L9′S |
2.20 ± 0.22 (n = 7) |
2.13 ± 0.17 (n = 7) |
3.70 ± 0.43 (n = 7) |
2.88 ± 0.24 (n = 7) |
8.82 ± 0.82 (n = 6) |
| DLG | VLG | SN | VTA | SC | |
| lynx1WT/ α6L9′S |
12.35 ± 0.98 (n = 6) |
8.06 ± 0.35 (n = 6) |
8.13 ± 0.26 (n = 5) |
8.24 ± 0.67 (n = 5) |
7.83 ± 0.39 (n = 6) |
| lynx1KO/ α6L9′S |
12.05 ± 1.31 (n = 6) |
8.91 ± 0.85 (n = 6) |
8.31± 0.60 (n = 5) |
8.06 ± 0.95 (n = 5) |
7.44 ± 0.73 (n = 7) |
Data are expressed as fmol of binding /mg wet weight of tissue. Region abbreviations are: NAc, nucleus accumbens; OT, olfactory tubercle; ST, striatum; opt, optic tracts; OPN, olivary pretectal nucleus; DLG, dorsal lateral geniculate; VLG, ventral lateral geniculate; SN, substantia nigra; VTA, ventral tegmental area; SC superior colliculus. Data were analyzed for effect of lynx1 for each region by t-test. No significant effects of lynx1 were found.