Table 1.

Various reported dosages of tranexamic acid, drainage times, and outcomes

Author [reference] (year)	Dosage	Drainage time	Outcomes
Nouraei et al. [2] (2013)	2 g in 500 mL of saline	5 min before sternal closure	Reduction in blood loss and frequency of transfusions
Patel et al. [3] (2017)	50 mg/kg in 20 mL of saline	20 min before sternal closure	Reduction in blood loss and frequency of transfusions
Taksaudom et al. [4] (2017)	1 g in 100 mL of saline	Before sternal closure until the patient was moved to the intensive care unita)	No significant difference in postoperative bleeding or frequency of blood transfusions
Kimenai et al. [5] (2016)	2 g in 200 mL of saline	1 min before sternal closure	No difference in postoperative bleeding or frequency of blood transfusions
Ali Shah et al. [6] (2016)	2.5 g in 250 mL of saline	Before sternal closurea)	Significant decrease in mean volume of postoperative bleeding

^a)The exact time of drainage of topical tranexamic acid was not reported.