Figure 3. Performance of the skCSD method for a ball-and-stick neuron with random synaptic stimulation for recordings with a laminar probe placed 50 μm away from the cell.

(A) The ground truth spatio-temporal membrane current density in time (x-axis) along the cell in the interval representation (y-axis). The lowest segment is the soma, where the visible high amplitude of potential is a consequence of spiking. To make the much less pronounced synaptic activity on the dendritic part visible, nonlinear color map was used. Panel (B) shows the lowest values of cross-validation and L1 error for the before-mentioned setups. Panels (C–E) present the best skCSD reconstruction in case of recording with 8, 32, and 128 electrodes. One can see how increasing the number and density of probes in the region improves the reconstruction quality until a certain level. CV error was used here to select the parameters leading to the best reconstructions.