Figure 4. CAPN2 promotes cell migratory, invasive and proliferative potential of RCC cells.
(A–C) Transwell migration assay and Matrigel invasion assay in 769-P and CAKI-1 cells with CAPN2 knockdown, in CAKI-2 cells with overexpression of CAPN2. (D) Growth curve analysis by CCK-8 assay showed the cell growth of 769-P, CAKI-1and CAKI-2 cells with CAPN2 knockdown or upregulation. Data represented the mean ± SD from three independent experiments, *P < 0.05.