Figure 4. Biomarker modulation by A438079 in pancreatic tumors.
(A–J) Effect of A438079 (50 ppm) on mRNA expression of P2X7R (A), Caspase-1 (B), Caspase-3 (C), IL-33 (D), NLRP1 (E), NLRP2 (F), NLRP6 (G), p21 (H), PCNA (I) and p53 (J) in pancreatic tumors from male p48Cre/+-KrasG12D/+ mice (statistical analysis is performed by t-test using graph pad prism, Mean ± SE; p < 0.05; ns; non-significant).