Table 1. HI antibody titers were detected at 2, 4, 6 and 8 wpv.

		HI
		2 wpv	4 wpv.	6 wpv	8 wpv
Group 1	pVAX1-HA	8	25.40	32a,b	12.70
Group 2	rCAV2-HA	32	41.78	98.05a,c	25.40
Group 3	Inactivated vaccine	32	47.95	120.82b,c	40.32
Group 4	pVAX1	< 2	< 2	< 2	< 2
Group 5	CAV2	< 2	< 2	< 2	< 2
Group 6	Adjuvant	< 2	< 2	< 2	< 2
Group 7	PBS	< 2	< 2	< 2	< 2
Group 8	NI	< 2	< 2	< 2	< 2

Notes:

Data are presented as geometric mean titer (n = 12, at 2, 4 and 6 wpv; n = 3, at 8 wpv).

Significant or extremely significant difference at p < 0.05 or p < 0.01, respectively.

NI = No immunization

CAV2-HA = live recombinant canine adenovirus 2 (CAV2) vector expressing the H3 hemagglutinin protein from the virus strain A/canine/Guangdong/01/2006(H3N2).

CAV2 = empty CAV2 vector

wpv = weeks post-vaccination

^a,b,c The same letter indicates the intergroup difference analysis.

^aThe difference is extremely significant (p < 0.01); ^bThe difference is extremely significant (p < 0.01); ^cThe difference is not significant (p > 0.05).