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. 2017 Sep 18;8(58):98215–98232. doi: 10.18632/oncotarget.21003

Figure 4. Expression of co-inhibitory receptors is reduced in CD4+ and CD8+ T cells stimulated with SEB in the presence of atorvastatin.

Figure 4

(A) Bar graphs showing expression of PD-1, LAG-3, TIM-3, CD160, CTLA-4 and CD244 by CD4+ and CD8+ T cells stimulated with SEB with or without atorvastatin (2 μg/ml) for 72hrs. (B) Co-expression of indicated co-inhibitory receptors in response to SEB-stimulation and atorvastatin treatment. (C) Representative dot plots indicating co-expression of co-inhibitory receptors in the presence and absence of atorvastatin. Results are representative of at least five independent experiments. Bar, mean ± one standard error. Unstimulated (cells only) cultures were used as negative controls.