Figure 1. COMP expression in prostate cancer cells is correlated with shorter time to recurrence.

Prostate cancer tissue microarrays were immunostained to detect COMP expression using a previously validated antibody, and the staining was scored 0, 1, 2, or 3 depending on the percentage of positive cells in each section (A). For statistical analyses, the samples were grouped into COMP negative (COMP^-) or COMP positive (COMP⁺). COMP expression did not affect overall survival (B), but significantly decreased the recurrence free survival (C), presence of metastases; (D), biochemical recurrence) of patients. Kaplan-Meier analyses with Breslows tests were used in B-D and p-values < 0.05 were considered significant.