Table 2. Ordered logistic regression analyses for liver fibrosis stage, F0-F4.
| Variable | Coefficient (95% confidence interval) | Standard error | Wald | P-value |
|---|---|---|---|---|
| univariate analysis | ||||
| LogeALT (IU/L) | 0.05-1.72 | 0.43 | 4.32 | 0.04 |
| LogeAST (IU/L) | 0.02-2.05 | 0.53 | 3.69 | 0.06 |
| LogeALB (g/dL) | 0.70-6.75 | 1.54 | 5.8 | 0.02 |
| LogeHBsAg(IU/mL) | 0.13-0.53 | 0.1 | 10.49 | 0.01 |
| LogeHBeAg(PEIU/mL) | 0.22-0.57 | 0.09 | 20.11 | <0.001 |
| Logeage(years) | 0.93-1.02 | 0.51 | 0.03 | 0.87 |
| LogeGGT (IU/L) | 0.02-0.85 | 0.22 | 3.4 | 0.07 |
| LogeTB (umol/dL) | 0.52-0.55 | 0.28 | 0.02 | 0.96 |
| LogeHBVDNA(copies/mL) | 1.57-1.76 | 0.85 | 0.01 | 0.91 |
| LogeWBC(×109) | 1.06-1.14 | 0.57 | 0.03 | 0.96 |
| Logeplatelet(×109) | 1.78-1.89 | 0.5 | 2.53 | 0.11 |
| Multivariate analysis | ||||
| LogeALT (IU/L) | 1.86(0.96-3.59) | 0.34 | 3.37 | 0.07 |
| LogeALB (g/dL) | 2.74(2.50-0.03) | 3.57 | 8.65 | 0.003 |
| LogeHBsAg(IU/mL | 0.55(0.36-0.86) | 0.22 | 7.04 | 0.008 |
| LogeHBeAg(PEIU/mL | 0.44(0.28-0.67) | 0.22 | 14.16 | <0.001 |
GGT, γ-glutamyltransferase; ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HBsAg, hepatitis B surface antigen; HBeAg, hepatitis B e antigen; WBC, white blood cell count; PLT, Platelet.