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. 2017 Oct 27;8(58):98953–98963. doi: 10.18632/oncotarget.22144

Figure 3. Collagen deposition and mucus overproduction is elevated in Sema3E deficient mice.

Figure 3

Lung tissue sections from saline- or HDM-exposed Sema3e−/− and WT mice were stained with Sirius red (A) and PAS (B) to determine collagen deposition and mucus hypersecretion, respectively (Scale bars: 100μm). Expression of remodeling genes, Col3 (C) and Muc5ac (D), in the lungs of Sema3e−/− and WT mice at the baseline or upon HDM challenge was studied by quantitative real-time PCR using specific primers (n= 5-6 per group, *P<0.05 and **P<0.01).