Table 1. Patients’ characteristics.
Parameters | N = 47 (%) |
---|---|
Gender | |
Male | 35 (74.5) |
Female | 12 (25.5) |
Age | |
> 30 | 15 (29.8) |
≤ 30 | 32 (70.2) |
ECOG PS score | |
≥ 2 | 11 (23.4) |
< 2 | 36 (76.6) |
B symptoms | |
Yes | 19 (40.4) |
No | 28 (59.6) |
Stage | |
I–II | 7 (14.9) |
III–IV | 40 (85.1) |
Bone marrow infiltration | |
Yes | 25 (53.2) |
No | 22 (46.8) |
LDH level | |
Elevated | 16 (34.0) |
Normal | 31 (66.0) |
Mediastinal mass | |
Yes | 42 (89.4) |
No | 5 (10.6) |
Chemotherapy regimens | |
ECOG 2993 | 5 (10.6) |
BFM-90 | 27 (57.4) |
HyperCVAD/MA | 12 (25.5) |
unspecified | 3 (6.5) |
Interim PET-CT | |
Positive | 19 (40.4) |
Negative | 28 (59.6) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; PS, performance status; LDH, lactate dehydrogenase; HyperCVAD/MA, fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone, alternating with high-dose methotrexate and cytarabine therapy.