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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Mol Carcinog. 2017 Aug 28;57(1):3–11. doi: 10.1002/mc.22714

Fig. 3. Impact of SFN and cisplatin on cell function.

Fig. 3

A/B HaCaT cells, growing in monolayer culture, were treated as indicated and cell number was determined at the indicated times. C/D/E HaCaT cell-derived eight day pre-formed spheroids were treated with cisplatin or SFN for 0 – 3 d and spheroid number per dish was determined. F/G HaCaT cells were seeded atop a layer of matrigel in a BD BioCoat chamber in the presence of the indicated agents and matrigel invaded cells were imaged and counted at 18 h. H Confluent monolayers of HaCaT cells were wounded with a pipette tip and wound closure was monitored rom 0 – 24 h. The graphical values are mean ± SEM, n = 3. The asterisks indicate a significant change compared to control, p < 0.001. The double asterisks indicate a significant reduction compare to the single treatment groups, p < 0.005.