(A) Pearson’s correlation coefficients between individual vital signs and chronological age across all, female, and male patients in three columns. Vital signs are sorted by descending order of their correlation coefficients with all patients. The smoothened trends of pulse pressure, systolic blood pressure and diastolic blood pressure across chronological age for females (blue) and males (green) are shown in panels B, C and D, respectively. The age range of patients used to produce these figures is 18 to 100 years.