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The differences between stress and strain dependent calcium release from the myofilaments on calcium transient and APD in the Grandi-Bers-Rice model. These results are consistent with the findings of Allen et al (Allen and Kurihara, 1980, 1982; Allen and Kentish, 1985). who showed that after steady state stretch quick release leads to an increase in cytosolic calcium transient and a significant loss in active force.
