Table 4.

Multivariable Cox models of PFS and OS

PFS (n=195**)				OS* (n=195**)
Factor	p-value	Hazard Ratio	95% CI on Hazard Ratio	Factor	p-value	Hazard Ratio	95% CI on Hazard Ratio
MYCN amplification	<0.0001	3.4	(2.2, 5.3)	MYCN amplification	0.001	2.0	(1.3, 2.9)
11q LOH	0.02	2.6	(1.2, 5.9)	11q LOH	0.01	2.8	(1.3, 6.3)
11q unknown	0.7	0.9	(0.5, 1.6)	11q unknown	0.6	1.2	(0.6, 2.1)

CI = confidence interval

^*“Era” was tested in the OS model but was not statistically significant.

^**Patients for whom both factors were unknown were excluded.