Fig. 6.

Example of new MS lesions detection in 12 months longitudinal analysis. Images (a) and (b) show one axial slice of T2-w image at baseline and follow-up, respectively. Image (c) shows the new MS lesions annotations performed by an expert (GT). Images (d), (e) and (f) show the segmentation of LR-DF, LR-NDF, and LR-NDFNB approaches, respectively. Notice that for this axial slice the LR-DF model could detect 7 lesions out of the 9 lesions in the GT. The two missed ones were actually detected in the adjacent slice.