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. 2017 Nov 16;14:656–668. doi: 10.1016/j.redox.2017.11.012

Fig. 6.

Fig. 6

CA prevented PDGF-BB-induced ROS production in VSMCs. VSMCs were pretreated with various concentrations (10, 50 and 100 μM) of CA for 6 h followed by stimulation with PDGF-BB (20 ng/mL) for 24 h. (A) ROS generation was evaluated by DHE fluorescence. (B) Relative ROS fluorescence intensity. (C) Represented images showing the protein expressions of NAD(P)H oxidase subunits p22phox, p47phox, NOX-2. The relative protein expressions of NAD(P)H oxidase subunits p22phox (D), p47phox (E), NOX-2 (F) were quantified. Values are mean ± SE. * P < 0.05 vs. Control, † P < 0.05 vs. PDGF-BB. n = 6 for each group.