Table 1.

Plasma parameters in mice fed control or methionine- and choline-deficient (MCD) diet for 1 and 2 weeks

Parameter	Control	MCD 1 week	MCD 2 weeks
TC (mg/dL)	91.1 ± 2.60	66.5** ± 3.85	52.3** ± 2.23
TG (mg/dL)	99.9 ± 15.6	31.6** ± 2.67	7.43** ± 1.71
AST (IU/L)	59.4 ± 18.6	367** ± 45.9	393** ± 108
ALT (IU/L)	25.1 ± 7.16	405** ± 67.1	256** ± 83.0
HDLC (mg/dL)	50.6 ± 1.61	36.1** ± 3.59	27.9** ± 2.08

Data are expressed as the mean ± SEM of six mice per group. Statistical differences were assessed using Dunnett’s test

TC total cholesterol, TG triglyceride, AST aspartate transaminase, ALT alanine aminotransferase, HDLC high-density lipoprotein cholesterol

**p < 0.01 compared with the control mice