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. 2017 Dec 1;8:1715. doi: 10.3389/fimmu.2017.01715

Figure 1.

Figure 1

Activation of HIV-specific T cells by HIV. As Trojan exosome, HIV-1 acquires the proteins necessary to mediate antigen presentation to T cells. Emerging from HIV-infected antigen-presenting cells, HIV particles are likely to display class II HLA molecules loaded with HIV-derived peptides. Thus, the virus could activate HIV-specific CD4 T cells, making them highly susceptible to infection by the virus.