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. 2017 Dec 1;7:494. doi: 10.3389/fcimb.2017.00494

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Copyright © 2017 Thangamani, Hermance, Santos, Slovak, Heinze, Widen and Kazimirova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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An overview of host gene modulation after 1 and 3 h of TBEV-infected Ixodes ricinus tick feeding. (A) The top IPA-generated network is shown for the TBEV-infected tick feeding loci at 1 h vs. the uninfected tick feeding loci at 1 h (B) The top IPA-generated network is shown for the TBEV-infected tick feeding loci at 3 h vs. the uninfected tick feeding loci at 3 h. (C) The top-IPA-generated network is shown for the TBEV-infected tick feeding loci at 3 h vs. TBEV-infected tick feeding loci at 1 h. Note: Red/pink represents upregulated genes, green represents down-regulated genes, and gray represents unchanged or insignificant genes.