Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 5;7:16914. doi: 10.1038/s41598-017-17193-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Core fucosylation was down-regulated and the pericyte-myofibroblast transition was inhibited upon FUT8 knockdown in vitro. Primary cultures of pericytes were incubated with TGFβ1 (10 ng/ml) for 24 or 48 h. (a) Representative bright-field images of morphological changes in pericytes, where black arrows indicate pericytes, and representative images of FUT8 (green), LCA (green), and α-SMA (red) staining are shown. Quantification is shown in the lower panel. (b) FUT8 and α-SMA levels were assessed using Western blot analyses. Quantification is shown in the lower panel. (c) Lectin blot analyses. Cell lysates were subjected to a lectin blot analysis using LCA. Representative data are shown. Quantification is shown in the lower panel. Scale bar, 50 μm. *P < 0.01, ^† P < 0.01. * and ^† indicate the comparison of the control group with the TGFβ1 group; # indicates the comparison of the FUT8 knockdown group with the TGFβ1 group.