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. 2017 Dec 5;7:16914. doi: 10.1038/s41598-017-17193-5

Figure 6.

Figure 6

The pericyte-myofibroblast transition was inhibited and RIF was reduced upon FUT8 knockdown in vivo. UUO models were established (n = 5). A recombinant adenovirus carrying the FUT8 shRNA was used to knock down FUT8 expression in vivo. (a) Representative images of Masson’s trichrome-stained and PAS-stained UUO kidney sections. (b) Representative images of dual staining for PDGFRβ (green) and α-SMA (red) staining and dual staining for PDGFRβ (green) and CD31 (red). Quantification of α-SMA staining is shown in the lower panel. Scale bar, 50 μm. *P < 0.01, # P < 0.01. *Indicates the comparison of the control group with the UUO group; #indicates the comparison of the FUT8 knockdown group with the UUO group.