Table 1.
Clinical characteristics of the 32 IgAN patients.
| Clinical Characteristics | T0 (n = 10) | T1 (n = 13) | T2 (n = 9) | P value |
|---|---|---|---|---|
| Age, median (IQR) (year) | 41 (27–51) | 38 (31–48) | 36 (34–53) | P1 = 0.477, P2 = 0.243 |
| Sex, male (%) | 5 (50) | 5 (38.5) | 4 (44.4) | — |
| IgAN Duration (month) | 18.3 ± 12.1 | 26.8 ± 27.8 | 22.4 ± 17.4 | P1 = 0.19, P2 = 0.275 |
| Systolic BP (mmHg) | 122.3 ± 10 | 125.9 ± 15.5 | 131 ± 13.3 | P1 = 0.264, P2 = 0.062 |
| Diastolic BP (mmHg) | 79.8 ± 6.7 | 79.8 ± 9.8 | 85.3 ± 12.5 | P1 = 0.495, P2 = 0.119 |
| Mean arterial BP (mmHg) | 94 ± 6.5 | 95.2 ± 10.9 | 100.6 ± 12 | P1 = 0.377, P2 = 0.074 |
| Twenty-four hour urinary protein (mg/24 h) | 621.3 ± 646.9 | 614 ± 386.6 | 1634.5 ± 890.9 | P1 = 0.487, P2 = 0.005* |
| Albumin (g/l) | 42.1 ± 3 | 39.5 ± 4.8 | 39.2 ± 4 | P1 = 0.077, P2 = 0.04* |
| Serum creatinine (umol/l) | 64.7 ± 12.9 | 71.8 ± 28.6 | 90.2 ± 32.8 | P1 = 0.239, P2 = 0.018* |
| Urine pH | 6.35 ± 0.7 | 6 ± 0.8 | 5.6 ± 0.4 | P1 = 0.176, P2 = 0.006* |
| eGFRMDRD (ml/min per 1.73 m2) | 115.7 ± 23.3 | 108.9 ± 39.4 | 85 ± 35.5 | P1 = 0.316, P2 = 0.018* |
| Urine specific gravity | 1.018 ± 0.008 | 1.019 ± 0.008 | 1.017 ± 0.005 | P1 = 0.371, P2 = 0.411 |
P 1, T1 vs T0, P 2, T2 vs T0, *P < 0.05.