Skip to main content
. 2017 Dec 1;11:33. doi: 10.3389/fnint.2017.00033

Table 1.

The identities of PNN neurons in the central nervous system.

CNS region Neuron type Location References
Cortex GABAergic inhibitory interneurons, inhibitory pyramidal cells positive for parvalbumin (Härtig et al., 1999), specifically the mbpC positive parvalbumin neurons (Rossier et al., 2015). Motor cortex, sensory cortex, prefrontal cortex, temporal cortex, layer 2-5 (Brückner et al., 1999), in visual cortex mostly 4-5, in mEC mostly 2-3 (Lensjø et al., 2017a). Brückner et al., 1999; Härtig et al., 1999; Rossier et al., 2015; Lensjø et al., 2017a
Amygdala Parvalbumin and calbindin positive inhibitory interneurons (Härtig et al., 1995) and excitatory neurons positive for CaMKII (Morikawa et al., 2017). Lateral and basolateral nuclei (Morikawa et al., 2017). Härtig et al., 1995; Morikawa et al., 2017
Hippocampus Basket cells and bistratified neurons with high parvalbumin levels (Yamada et al., 2015). Excitatory pyramidal cells (Carstens et al., 2016). Highest in CA2 (Lensjø et al., 2017a) CA1 and CA3 (Kochlamazashvili et al., 2010), dentate gyrus (Jansen et al., 2017). Kochlamazashvili et al., 2010; Yamada et al., 2015; Carstens et al., 2016; Jansen et al., 2017; Lensjø et al., 2017a
Cerebellum Excitatory Golgi neurons (Carulli et al., 2006) and Purkinje cells (Mabuchi et al., 2001) positive for parvalbumin. Cerebellar cortex (Mabuchi et al., 2001) and nuclei (Lafarga et al., 1984; Blosa et al., 2016). Lafarga et al., 1984; Mabuchi et al., 2001; Carulli et al., 2006; Blosa et al., 2016
Spinal cord Large interneurons, 30% of motoneurons (Smith et al., 2015). 30% of motoneurons in ventral horn, 20% of neurons in the dorsal horn (Galtrey et al., 2008). Galtrey et al., 2008; Smith et al., 2015