Table 2.

Serum Levels of laboratory markers.

	CCA patients median [range], number of analyzed patients	PSC patients median [range], number of analyzed patients	Healthy controls median [range], number of analyzed patients
CEA [µg/l]	2.95 [0.71–110.4], n = 92	1.15 [0.2–5.1], n = 20	1.25 [0.3–6.3], n = 50
CA 19–9 [U/ml]	78.4 [0.5–38092], n = 99	15.95 [2.3–78.4], n = 24	5.4 [0–44.1], n = 50
AFP [ng/ml]	4 [1–177.8], n = 49	1.95 [1–8.7], n = 20	—
WBC [cells/nl]	7.95 [2.9–21.8], n = 190	6.8 [3.3–12.4], n = 23	—
CRP [mg/l]	14.95 [0–230], n = 180	6.4 [0.6–127], n = 20	—
AST [U/l]	45 [15–1587], n = 189	67 [16–108], n = 22	28 [20–78], n = 50
ALT [U/l]	46.5 [10–1097], n = 136	75.5 [22–224], n = 24	20 [5–82], n = 50
GGT [U/l]	293.5 [13–2015], n = 184	265 [18–1223], n = 24	17 [8–120], n = 50
ALP [U/l]	215 [45–1655], n = 184	248 [81–694], n = 24	65 [36–102], n = 50
Bilirubin [mg/dl]	0.9 [0.2–21.49], n = 189	0.89 [0.36–11.07], n = 22	0.41 [0.1–1.46], n = 50
Creatinine [mg/dl]	0.8 [0.4–1.9], n = 190	0.78 [0.3–2.42], n = 23	—
Sodium [mmol/l]	140 [121–146], n = 189	139 [136–144], n = 23	—
Potassium [mmol/l]	4.3 [2.9–7], n = 189	4.25 [3.6–5.3], n = 22	—
Calcium [mmol/l]	2.3 [1.78–5.43], n = 182	2.35 [2.09–2.52], n = 21	—
Haemoglobin [g/l]	12.55 [7.8–19.9], n = 190	14.4 [8.3–16.5], n = 23	—
Platelets [cells/nl]	276.5 [9–931], n = 190	261 [118–417], n = 23	—

WBC: white blood cell count, CRP: C-reactive protein, AST: aspartate transaminase, ALT: alanine transaminase, GGT: γ-Glutamyl transpeptidase, ALP: alkaline phosphatase, CEA: carcinoembryonic antigen, CA 19-9: carbohydrate-Antigen 19-9, AFP: Alpha-fetoprotein.