Table 1.
Demographic and clinical features of 50 patients with NSIP.
| NSIP (n = 50) | |
|---|---|
| Demographics | |
| Age (years) | 49.2 ± 10.7 |
| Male, N (%) | 17/50 (34) |
| Duration from disease onset to biopsy (months), median (range) | 6 (1.0~36) |
| Follow-up time (months), median (range) | 75.5 (8~147) |
| Clinical manifestations, N (%) | |
| Dry eyes or dry mouth | 8/50(16%) |
| Fever | 6/50 (12%) |
| Arthralgia | 9/50 (18%) |
| Skin rash | 6/50 (12%) |
| Raynaud’s phenomenon | 3/50 (6%) |
| Weight loss | 4/50 (8%) |
| Chest pain | 4/50 (8%) |
| Cough | 37/50 (74%) |
| Dyspnea | 40/50 (80%) |
| Crackles | 37/50 (74%) |
| Clubbing finger | 17/50 (34%) |
| Clinical subtype of NSIP, N (%) | |
| CTD-NSIP | 20 |
| Antibody positive NSIP | 12 |
| Idiopathic NSIP | 18 |
| Lab testing | |
| ESR, mm/h | 21.8 ± 20.0 |
| PaO2, mmHg | 77.7 ± 13.3 |
| PCO2, mmHg | 37.9 ± 8.4 |
| Baseline pulmonary function tests | |
| FEV1.0, % predicted | 68.6 ± 15.4 |
| FVC, % predicted | 67.1 ± 15.2 |
| TLC, % predicted | 76.8 ± 14.1 |
| DLCO, % predicted | 56.4 ± 16.8 |
| Baseline chest CT findings, N (%) | |
| Ground glass opacity | 33/50 (66) |
| Patchy opacity | 35/50 (70) |
| Reticular opacity | 32/50 (64) |
| Traction bronchiectasis | 16/50 (32) |
| Pleural thickening | 7/50 (14) |