Table 1.
Over- and under-expressed genes in 24 h CSCL in vivo implant compared with CL profiled on pro-inflammatory cytokines and receptors PCR array.
| Symbol | Refseq | Description | Fold Change | p-value |
|---|---|---|---|---|
| Over-expressed genes in CSCL | ||||
| Aimp1 | NM_053757 | Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | 2,0423 | 0,034437 |
| Ccl12 | NM_001105822 | Chemokine (C-C motif) ligand 12 | 3,5857 | 0,013407 |
| Ccl2 | NM_031530 | Chemokine (C-C motif) ligand 2 | 2,6097 | 0,053334 |
| Ccl5 | NM_031116 | Chemokine (C-C motif) ligand 5 | 2,1609 | 0,07928 |
| Ccr1 | NM_020542 | Chemokine (C-C motif) receptor 1 | 2,5869 | 0,001323 |
| Ccr2 | NM_021866 | Chemokine (C-C motif) receptor 2 | 3,147 | 0,008204 |
| Ccr4 | NM_133532 | Chemokine (C-C motif) receptor 4 | 2,1166 | 0,253888 |
| Ccr6 | NM_001013145 | Chemokine (C-C motif) receptor 6 | 3,2838 | 0,050775 |
| Ccr8 | XM_236704 | Chemokine (C-C motif) receptor 8 | 3,4874 | 0,005749 |
| Cx3cl1 | NM_134455 | Chemokine (C-X3-C motif) ligand 1 | 2,0435 | 0,011638 |
| Cxcl11 | NM_182952 | Chemokine (C-X-C motif) ligand 11 | 2,406 | 0,027316 |
| Cxcl9 | NM_145672 | Chemokine (C-X-C motif) ligand 9 | 2,0105 | 0,06048 |
| Cxcr5 | NM_053303 | Chemokine (C-X-C motif) receptor 5 | 3,0484 | 0,001469 |
| Faslg | NM_012908 | Fas ligand (TNF superfamily, member 6) | 2,9559 | 0,002851 |
| Il1r1 | NM_013123 | Interleukin 1 receptor, type I | 3,3212 | 0,034378 |
| Il21 | NM_001108943 | Interleukin 21 | 2,5714 | 0,130204 |
| Il3 | NM_031513 | Interleukin 3 | 3,4003 | 0,028243 |
| Il33 | NM_001014166 | Interleukin 33 | 2,2283 | 0,205627 |
| Il4 | NM_201270 | Interleukin 4 | 2,4614 | 0,046653 |
| Il5ra | NM_053645 | Interleukin 5 receptor, alpha | 2,3901 | 0,009556 |
| Il6r | NM_017020 | Interleukin 6 receptor | 2,478 | 0,004808 |
| Il6st | NM_001008725 | Interleukin 6 signal transducer | 2,2308 | 0,001629 |
| Il7 | NM_013110 | Interleukin 7 | 3,5534 | 0,000298 |
| Lta | NM_080769 | Lymphotoxin alpha (TNF superfamily, member 1) | 2,9841 | 0,025761 |
| Spp1 | NM_012881 | Secreted phosphoprotein 1 | 2,3364 | 0,109091 |
| Tnfrsf11b | NM_012870 | Tumor necrosis factor receptor superfamily, member 11b | 3,33 | 0,172409 |
| Under-expressed genes in CSCL | ||||
| Il11 | NM_133519 | Interleukin 11 | 0,2471 | 0,226938 |
| Il1a | NM_017019 | Interleukin 1 alpha | 0,1181 | 0,009542 |
| Il2rg | NM_080889 | Interleukin 2 receptor, gamma | 0,3161 | 0,349324 |
| Tnfsf14 | NM_001191803 | Tumor necrosis factor (ligand) superfamily, member 14 | 0,1531 | 0,011446 |