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. 2017 Dec 5;7:16993. doi: 10.1038/s41598-017-17027-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The integral sum of Gaussian energy profiles used to fit experimental curve within 1000–1140 cm⁻¹. (a) The calibration curve obtained after adding integral values of energy profiles used to fit experimental curves. The sum of integral values of control groups cluster within the approximate range 12–14, B16 covers the range 15–17 and EL4 covers 15–18. (b) Bar graph representation of average value of integral sum which shows significant difference between control and tumorigenic case.