Table 1.
Characteristics of study population (n = 65,057) from Karolinska Mammography Project for Risk Prediction of Breast Cancer (KARMA), recruited between 2011 and 2013.
| Age at entry (years), mean (SD) | 55.1 (10.0) | |
| Age at menarche (years), mean (SD) | 13.1 (1.5) | |
| Irregular menstrual cycle during adult life, n (%) | 7626 (11.3) | |
| Physical activity at age 18 (h/week), n (%) | ||
| 0 | 2749 (4.2) | |
| <1 | 7294 (11.2) | |
| 1–2 | 17207 (26.4) | |
| 3–5 | 17377 (26.7) | |
| 5+ | 14570 (22.4) | |
| Education, n (%) | ||
| Elementary | 7518 (11.6) | |
| Intermediate | 17795 (27.4) | |
| College | 30012 (46.1) | |
| Other | 9559 (14.7) | |
| Number of children, n (%) | ||
| 0 | 8304 (12.8) | |
| 1 | 9622 (14.8) | |
| 2 | 30996 (47.6) | |
| 3+ | 16126 (24.8) | |
| Ever regular smoke, n (%) | 34423 (52.9) | |
| Body mass index at questionnaire (BMI, kg/m2), mean (SD) | 25.2 (4.2) | |
| Body size at age 7, n (%) | ||
| 1 | 15074 (23.2) | |
| 2 | 20032 (30.8) | |
| 3 | 14091 (21.7) | |
| 4 | 9433 (14.5) | |
| 5 | 4592 (7.1) | |
| 6 | 1511 (2.3) | |
| 7 | 260 (0.4) | |
| 8 | 53 (0.1) | |
| 9 | 11 (<0.1) | |
| Cancer outcomes, n (%) | Average age at diagnosis (years), mean (SD) | |
| Breast | 2733 (4.2) | 55.4 (10.1) |
| Cervical cancer | 222 (0.3) | 41.9 (10.9) |
| Uterine | 259 (0.4) | 58.8 (7.5) |
| Melanoma | 551 (0.8) | 47.8 (13.1) |
| Colon | 235 (0.4) | 55.0 (14.3) |
| Non-cancer outcomes, n (%) | ||
| Depression | 9642 (14.8) | 41.5 (11.4) |
| Anorexia | 498 (0.8) | 19.6 (7.1) |
| Bulimia | 318 (0.5) | 25.3 (9.7) |
| PCOS | 217 (0.3) | 29.4 (6.8) |
| Ovarian cyst | 4325 (6.6) | 36.1 (12.7) |
| Diabetes | 1805 (2.8) | 48.9 (15.5) |
| Hypertension | 12695 (19.5) | 50.8 (11.7) |
| Hyperlipidemia | 6869 (10.6) | 54.3 (10.1) |
| Stroke | 689 (1.1) | 54.5 (11.8) |
| Heart failure | 369 (0.6) | 56.8 (13.0) |
| Myocardial infarction | 479 (0.7) | 56.4 (9.4) |
| Angina pectoris | 570 (0.9) | 55.2 (10.7) |