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. 2017 Aug 7;36(48):6701–6711. doi: 10.1038/onc.2017.267

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Copyright © 2017 The Author(s)

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High levels of LSD1 and SESN2 expression are mutually exclusive in NB. (a) Kaplan–Meier analysis shows that high SESN2 gene expression is associated with better survival in NB patients. Patients are grouped by the optimal cutoff of LSD1 and SESN2 expression. The ‘raw P’ indicates the uncorrected P-value, and the ‘bonf P’ indicates the P-value corrected for multiple tests according to the Bonferroni method. (b) Changes in expression for LSD1 and Sestrin2 in ganglioneuroblastoma (GNB), ganglioneuroma (GN), NB and NB post chemotherapy (NB p.c.). (c) Correlation between the expression values of SESN2 and LSD1 in NB tumors (Pearson’s correlation coefficient is shown).