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. 2017 Nov 8;6(11):e100. doi: 10.1038/emi.2017.88

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Phylogenetic trees were generated from the full-length HBV genome in patient S08 by CBS (A) and TGS (B). Strains within different clusters were marked with different colors. clone-based sequencing, CBS; hepatitis B virus, HBV; third-generation sequencing, TGS.