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Schematic overviews of the genomic organizations around replication origins ori1 (A) and ori2 (B). The core origins are comprised of (i) noncoding sequences (oriC) containing the origin repeat boxes (ORBs) and DNA unwinding elements (DUE) and (ii) a paralog of an orc gene. The gene designations of the adjacent genes (HVO_no.) are included. The regions that were selected for deletions are indicated.
